Progression of mycosis fungoides is associated with increasing cutaneous expression of interleukin-10 mRNA.

@article{Asadullah1996ProgressionOM,
  title={Progression of mycosis fungoides is associated with increasing cutaneous expression of interleukin-10 mRNA.},
  author={Khusru Asadullah and W D Doecke and Antje Haeu\ssler and Wolfram Sterry and H. D. Volk},
  journal={The Journal of investigative dermatology},
  year={1996},
  volume={107 6},
  pages={833-7}
}
Cytokines are believed to play an important role in the pathogenesis of cutaneous T cell lymphoma. Data regarding the local cytokine pattern in mycosis fungoides (MF) are partly conflicting. Recent studies have suggested a shift from type 1 to type 2 cytokine pattern because IL-4 and IL-5 mRNA have been more frequently detected in lesions of advanced stages. Another study has described a type 1 cytokine pattern in MF lesions. None of the previous studies of cytokine mRNA expression in MF… CONTINUE READING
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