Progression of drug exanthemas to serious drug eruptions: A retrospective review identifying early determinants.

@article{Manrquez2016ProgressionOD,
  title={Progression of drug exanthemas to serious drug eruptions: A retrospective review identifying early determinants.},
  author={Juan Jorge Manr{\'i}quez and Romina Andino-Navarrete and Karina Cataldo-Cerda and Camila Downey and Daniela Berroeta},
  journal={The Australasian journal of dermatology},
  year={2016},
  volume={57 3},
  pages={e83-7}
}
BACKGROUND/OBJECTIVES Maculo-papular drug exanthema (MPE) is the most common type of cutaneous adverse drug reaction (CAR). Exanthematous macules and papules may also be the initial presentation of severe CAR (SCAR). We aimed to identify characteristics associated with the diagnosis of SCAR in CAR-hospitalised patients. METHODS This cross-sectional study was performed in a tertiary hospital in Chile. All CAR patients who were initially evaluated for exanthematous macules and papules were… CONTINUE READING

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