Progression of chromosome abnormalities after radiation therapy in a patient with Askin's tumor.

@article{Sawyer1990ProgressionOC,
  title={Progression of chromosome abnormalities after radiation therapy in a patient with Askin's tumor.},
  author={Jeffrey R. Sawyer and William M. Chadduck and M Keltzel},
  journal={Cancer genetics and cytogenetics},
  year={1990},
  volume={47 1},
  pages={89-94}
}
A patient previously reported to have Ewing's sarcoma showed a t(11;22) (q23;q11) and spontaneous expression of fra(11)(q23) [1]. Subsequent review of pathologic specimen indicated, however, that it was an Askin's tumor. Reciprocal translocations of chromosomes 11 and 22 are the most common cytogenetic abnormalities in Ewing's sarcoma and the related Askin… CONTINUE READING