Progression of asymptomatic peripheral artery disease over 1 year.

  title={Progression of asymptomatic peripheral artery disease over 1 year.},
  author={Emile R. Mohler and Warner P Bundens and Julie O. Denenberg and Elizabeth Medenilla and William Robert Hiatt and Michael H. Criqui},
  journal={Vascular medicine},
  volume={17 1},
The pathophysiology and time course of an individual converting from asymptomatic peripheral artery disease (PAD) to symptomatic claudication is unclear. The objectives of this study were: (1) to characterize the extent of atherosclerotic disease in individuals with an abnormal ankle-brachial index (ABI), but without claudication; and over 1 year of follow-up to (2) evaluate the progression of PAD using ultrasound imaging, (3) determine changes in the ABI and leg pain symptoms, and (4… CONTINUE READING