Progression of astrocytomas and meningiomas: an evaluation in vitro.

  title={Progression of astrocytomas and meningiomas: an evaluation in vitro.},
  author={Lea Maes and J P O Kalala and Maria Cornelissen and Leo I F J M De Ridder},
  journal={Cell proliferation},
  volume={40 1},
OBJECTIVES/BACKGROUND In biological terms, progression means that malignancy increases as genetic mutations accumulate leading to increased proliferation and invasion capacity. By verifying the proliferation capacity, human telomerase reverse transcriptase (hTERT) expression and in vitro invasion, in a group of highly malignant glioblastomas, benign meningiomas and astrocytomas, at the initial stage of progression, we have analysed putative progression in vitro for proliferation and telomerase… CONTINUE READING