Progression of B-Chronic Lymphocytic Leukemia Cells Induced to Differentiate by TPA

  • By Mats Carlsson, Thomas H. T246tterman, +1 author Kenneth Nilsson
  • Published 2005
The cell cycle transition and differentiation-associated surface antigen expression was studied in a clone of B cell chnonic lymphocytic leukemia (B-CLL) with phenotypic pnopenties similar to those of resting B lymphocytes. Diffenentiation was induced with TPA (12-0-tetnadecanoylphorbol-13-acetate) and defined and quantitated by monphological and functional… CONTINUE READING