Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.

Abstract

The poor prognosis of pancreatic cancer patients using currently available therapies mandates novel therapeutics that combine anti-neoplastic potency with toxicity-minimizing cancer specificity. Employing an overlapping pathway screen to identify genes exhibiting coordinated expression as a consequence of terminal cell differentiation and replicative… (More)

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Cite this paper

@article{Chan2008ProgressionEG, title={Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.}, author={Isaac S. Chan and Irina V Lebedeva and Zao-zhong Su and Devanand Sarkar and Kristoffer C Valerie and P. Brian Fisher}, journal={Journal of cellular physiology}, year={2008}, volume={215 2}, pages={401-9} }