Progression after chronic manganese exposure.

  title={Progression after chronic manganese exposure.},
  author={C-C Huang and Chin Lu and N. S. Chu and Fred Hochberg and David Lilienfeld and Warren C Olanow and Donald B. Calne},
  volume={43 8},
We report a longitudinal follow-up study on six patients with chronic manganese-induced parkinsonism following cessation of manganese exposure. Compared with the 1987 study, their parkinsonian symptoms showed a slow progression, particularly in gait disturbances such as freezing during turning and walking backward with retropulsion. The mean disability scores on the King's College Hospital Rating Scale were 15.0 +/- 4.2 in 1987 and 28.3 +/- 6.7 in 1991 (p = 0.003, paired t test). Review of the… CONTINUE READING


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