Progress towards in vivo use of siRNAs.

  title={Progress towards in vivo use of siRNAs.},
  author={Mark A. Behlke},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  volume={13 4},
  • Mark A. Behlke
  • Published 2006 in
    Molecular therapy : the journal of the American…
RNA interference (RNAi) has become the method of choice to suppress gene expression in vitro. It is also emerging as a powerful tool for in vivo research with over 90 studies published using synthetic small interfering RNAs in mammals. These reports demonstrate the potential for use of synthetic small interfering RNAs (siRNAs) as therapeutic agents… CONTINUE READING