Progress towards gene therapy for cystic fibrosis

  title={Progress towards gene therapy for cystic fibrosis},
  author={S. Tate and S. Elborn},
  journal={Expert Opinion on Drug Delivery},
  pages={269 - 280}
  • S. Tate, S. Elborn
  • Published 2005
  • Biology, Medicine
  • Expert Opinion on Drug Delivery
  • A decade ago it was widely anticipated that cystic fibrosis would be one of the first diseases to be treated by gene therapy. The difficult hurdle of cloning the responsible gene had been accomplished, its function was established and the lung appeared readily accessible for gene replacement. Since the first clinical trials for cystic fibrosis lung disease in the early 1990s it has become increasingly apparent that successful lung-directed gene therapy is significantly more complex than was… CONTINUE READING
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