Progress towards development of a vaccine for amebiasis.

  title={Progress towards development of a vaccine for amebiasis.},
  author={Samuel L. Stanley},
  journal={Clinical microbiology reviews},
  volume={10 4},
The application of molecular biologic techniques over the past decade has seen a tremendous growth in our knowledge of the biology of Entamoeba histolytica, the causative agent of amebic dysentery and amebic liver abscess. This approach has also led to the identification and structural characterization of three amebic antigens, the serine-rich Entamoeba histolytica protein (SREHP), the 170-kDa subunit of the Gal/GalNAc binding lectin, and the 29-kDa cysteine-rich protein, which all show promise… CONTINUE READING
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Immunogenicity of the recombinant serine rich Entamoeba histolytica protein (SREHP) in African green monkeys

  • S. L. Stanley, Jr., +6 authors F. B. Cogswell
  • Vaccine
  • 1995
Highly Influential
3 Excerpts

Cloning and expression of a membrane antigen of Entamoeba histolytica possessing multiple tandem repeats

  • S. L. Stanley, Jr., A. Becker, C. Kunz-Jenkins, L. Foster, E. Li
  • Proc. Natl. Acad. Sci. USA
  • 1990
Highly Influential
5 Excerpts

Expression of the serine rich Entamoeba histolytica protein (SREHP) in the avirulent vaccine strain Salmonella typhi TY2 4297 (Dcya Dcrp Dasd): safety and immunogenicity in mice

  • T. Zhang, S. L. Stanley, Jr.
  • Vaccine, in press
  • 1997

Human anti-amebic antibodies provide protection against amebic liver abscess formation in the SCID mouse

  • K. B. Seydel, K. Braun, T. Zhang, T.F.H.G. Jackson, S. L. Stanley, Jr.
  • Am. J. Trop. Med. Hyg
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