Progress toward effective treatments for human photoreceptor degenerations.

  title={Progress toward effective treatments for human photoreceptor degenerations.},
  author={Edwin M. Stone},
  journal={Current opinion in genetics & development},
  volume={19 3},
Mutations in several dozen genes have been shown to cause inherited photoreceptor degeneration in humans and it is likely that mutations in several dozen more will eventually be identified. Careful study of these genes has provided insight into the cellular and molecular mechanisms of human photoreceptor disease and has accelerated the development of a number of different classes of therapy including: nutritional supplementation, toxin avoidance, small-molecule drugs, large-molecule drugs, gene… CONTINUE READING