Progress toward an integrated understanding of Parkinson’s disease

  title={Progress toward an integrated understanding of Parkinson’s disease},
  author={Maxime W. C. Rousseaux and Joshua M Shulman and Joseph Jankovic},
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, affecting over 10 million individuals worldwide. While numerous effective symptomatic treatments are currently available, no curative or disease-modifying therapies exist. An integrated, comprehensive understanding of PD pathogenic mechanisms will likely address this unmet clinical need. Here, we highlight recent progress in PD research with an emphasis on promising translational findings… CONTINUE READING
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Results from a phase 1 b multiple ascendingdose study of PRX 002 , an antialpha - synuclein monoclonal antibody , in patients with Parkinson ’ s disease

  • J Jankovic, I Godman, B Safirstein
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  • 2017

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