Progress toward an efficient panel of SNPs for ancestry inference.

Abstract

Many panels of ancestry informative single nucleotide polymorphisms have been proposed in recent years for various purposes including detecting stratification in biomedical studies and determining an individual's ancestry in a forensic context. All of the panels have limitations in their generality and efficiency for routine forensic work. Some panels have used only a few populations to validate them. Some panels are based on very large numbers of SNPs thereby limiting the ability of others to test different populations. We have been working toward an efficient and globally useful panel of ancestry informative markers that is comprised of a small number of highly informative SNPs. We have developed a panel of 55 SNPs analyzed on 73 populations from around the world. We present the details of the panel and discuss its strengths and limitations.

DOI: 10.1016/j.fsigen.2014.01.002
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@article{Kidd2014ProgressTA, title={Progress toward an efficient panel of SNPs for ancestry inference.}, author={Kenneth K. Kidd and William C. Speed and Andrew J. Pakstis and Manohar R . Furtado and Rixun Fang and Abeer Madbouly and Martin Maiers and Mridu Middha and Françoise R. Friedlaender and Judith R. Kidd}, journal={Forensic science international. Genetics}, year={2014}, volume={10}, pages={23-32} }