Progress in the treatment of acute promyelocytic leukemia: optimization and obstruction.

@article{Li2014ProgressIT,
  title={Progress in the treatment of acute promyelocytic leukemia: optimization and obstruction.},
  author={Junmin Li and Hongming Zhu and Jiong Yu Hu and Jianqing Mi and Sai-juan Chen and Zhu Chen and Zhenyi Wang},
  journal={International journal of hematology},
  year={2014},
  volume={100 1},
  pages={38-50}
}
The past three decades have witnessed a great progress in the treatment of acute promyelocytic leukemia (APL). The current application of all-trans retinoic acid, arsenic trioxide (ATO), and anthracycline-based chemotherapies has been proved to be highly effective. Based on the risk factors of APL, optimization of the treatment emphasizes the role of ATO in induction, consolidation and maintenance therapy as a substitute to chemotherapy in low- and intermediate-risk patients, and in potential… CONTINUE READING