Progress in the research of S-adenosyl-l-methionine production

@article{Chu2012ProgressIT,
  title={Progress in the research of S-adenosyl-l-methionine production},
  author={Ju Chu and Jiangchao Qian and Yingping Zhuang and Siliang Zhang and Yourong Li},
  journal={Applied Microbiology and Biotechnology},
  year={2012},
  volume={97},
  pages={41-49}
}
This minireview mainly aims at the study of S-adenosyl-l-methionine (SAM) production by microbial fermentation. A brief introduction of the biological role and application of SAM was presented. In general, SAM production can be improved by breeding of the producing strain through the conventional mutation or genetic engineering approach in the molecular or cellular scale, by optimization of culture conditions in the cellular scale or bioreactor engineering scale, or by multiscale approach. The… CONTINUE READING

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