Progress in pharmacotherapy of borderline disorders. A double-blind study of amitriptyline, haloperidol, and placebo.

@article{Soloff1986ProgressIP,
  title={Progress in pharmacotherapy of borderline disorders. A double-blind study of amitriptyline, haloperidol, and placebo.},
  author={Paul H Soloff and Abraham George and R. Swami Nathan and Prof. Dr. med. K. -D. Schulz and R. Eng. Frederico Ulrich and James M. Perel},
  journal={Archives of general psychiatry},
  year={1986},
  volume={43 7},
  pages={691-7}
}
In symptomatic patients with borderline disorder, we conducted a double-blind, placebo-controlled trial of haloperidol and amitriptyline hydrochloride to test the differential efficacy of medication against the affective and schizotypal symptoms that characterize the disorder. Sixty-one patients, diagnosed by the Diagnostic Interview for Borderline of Gunderson et al, completed randomized trials of haloperidol (n = 21), amitriptyline (n = 20), and placebo (n = 20). Medications were given in… CONTINUE READING