Progress in developing cationic vectors for non-viral systemic gene therapy against cancer.

@article{Morille2008ProgressID,
  title={Progress in developing cationic vectors for non-viral systemic gene therapy against cancer.},
  author={Marie Morille and Catherine Passirani and Arnaud Vonarbourg and Anne Clavreul and J Beno{\^i}t},
  journal={Biomaterials},
  year={2008},
  volume={29 24-25},
  pages={3477-96}
}
Initially, gene therapy was viewed as an approach for treating hereditary diseases, but its potential role in the treatment of acquired diseases such as cancer is now widely recognized. The understanding of the molecular mechanisms involved in cancer and the development of nucleic acid delivery systems are two concepts that have led to this development. Systemic gene delivery systems are needed for therapeutic application to cells inaccessible by percutaneous injection and for multi-located… CONTINUE READING
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