Progress and prospects in rat genetics: a community view

@article{Aitman2008ProgressAP,
  title={Progress and prospects in rat genetics: a community view},
  author={T. Aitman and J. Critser and E. Cuppen and A. Dominiczak and X. M. Fern{\'a}ndez-Su{\'a}rez and J. Flint and D. Gauguier and A. Geurts and Michael Gould and P. Harris and R. Holmdahl and N. Hubner and Z. Izsv{\'a}k and H. Jacob and T. Kuramoto and A. Kwitek and A. Marrone and T. Mashimo and C. Moreno and J. Mullins and L. Mullins and T. Olsson and M. Pravenec and L. Riley and K. Saar and T. Serikawa and J. Shull and C. Szpirer and S. Twigger and B. Voigt and K. Worley},
  journal={Nature Genetics},
  year={2008},
  volume={40},
  pages={516-522}
}
The rat is an important system for modeling human disease. Four years ago, the rich 150-year history of rat research was transformed by the sequencing of the rat genome, ushering in an era of exceptional opportunity for identifying genes and pathways underlying disease phenotypes. Genome-wide association studies in human populations have recently provided a direct approach for finding robust genetic associations in common diseases, but identifying the precise genes and their mechanisms of… Expand
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