Progress and prospects in rat genetics: a community view

@article{Aitman2008ProgressAP,
  title={Progress and prospects in rat genetics: a community view},
  author={Timothy J. Aitman and John Kenneth Critser and Edwin Cuppen and Anna F. Dominiczak and Xos{\'e} M. Fern{\'a}ndez-Su{\'a}rez and Jonathan Flint and Dominique Gauguier and Aron M. Geurts and Michael Gould and Peter C. Harris and Rikard Holmdahl and Norbert Hubner and Zsuzsanna Izsv{\'a}k and Howard J. Jacob and Takashi Kuramoto and Anne E. Kwitek and Anna Marrone and Tomoji Mashimo and Carol Moreno and John J. Mullins and Linda J. Mullins and Tomas P. Olsson and Michal Pravenec and Lela K. Riley and Kathrin Saar and Tadao Serikawa and James D Shull and Claude Szpirer and Simon N. Twigger and Birger Voigt and Kim C. Worley},
  journal={Nature Genetics},
  year={2008},
  volume={40},
  pages={516-522}
}
The rat is an important system for modeling human disease. Four years ago, the rich 150-year history of rat research was transformed by the sequencing of the rat genome, ushering in an era of exceptional opportunity for identifying genes and pathways underlying disease phenotypes. Genome-wide association studies in human populations have recently provided a direct approach for finding robust genetic associations in common diseases, but identifying the precise genes and their mechanisms of… 

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