Progress and novel strategies in vaccine development and treatment of anthrax.

@article{Chitlaru2011ProgressAN,
  title={Progress and novel strategies in vaccine development and treatment of anthrax.},
  author={Theodor Chitlaru and Zeev Altboum and Shaul Reuveny and Avigdor Shafferman},
  journal={Immunological reviews},
  year={2011},
  volume={239 1},
  pages={221-36}
}
The lethal anthrax disease is caused by spores of the gram-positive Bacillus anthracis, a member of the cereus group of bacilli. Although the disease is very rare in the Western world, development of anthrax countermeasures gains increasing attention due to the potential use of B. anthracis spores as a bio-terror weapon. Protective antigen (PA), the non-toxic subunit of the bacterial secreted exotoxin, fulfills the role of recognizing a specific receptor and mediating the entry of the toxin… CONTINUE READING

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