Progranulin gene variability influences the risk for bipolar I disorder, but not bipolar II disorder.

@article{Galimberti2014ProgranulinGV,
  title={Progranulin gene variability influences the risk for bipolar I disorder, but not bipolar II disorder.},
  author={Daniela Galimberti and Cecilia Prunas and Riccardo Augusto Paoli and Bernardo Dell'osso and Chiara Fenoglio and Chiara Villa and Carlotta Palazzo and Michela Cigliobianco and Giulia Camuri and Maria Serpente and Elio Scarpini and Alfredo Carlo Altamura},
  journal={Bipolar disorders},
  year={2014},
  volume={16 7},
  pages={769-72}
}
OBJECTIVE Recent data have shown that genetic variability in the progranulin (GRN) gene may contribute to the susceptibility to developing bipolar disorder (BD). However, in regard to patients with BD, no information is available on the role of genetic variability and plasma progranulin levels in different types of this disorder. METHODS In this study, we performed an association analysis of GRN in an Italian population consisting of 134 patients with BD and 232 controls to evaluate… CONTINUE READING

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