Programming of Obesity and Comorbidities in the Progeny: Lessons from a Model of Diet-Induced Obese Parents

@inproceedings{Ornellas2015ProgrammingOO,
  title={Programming of Obesity and Comorbidities in the Progeny: Lessons from a Model of Diet-Induced Obese Parents},
  author={Fernanda Ornellas and Vanessa Souza-Mello and Carlos Alberto Mandarim-de-Lacerda and M{\'a}rcia Barbosa {\'A}guila},
  booktitle={PloS one},
  year={2015}
}
AIM To determine the impact of paternal obesity, maternal obesity or the combination of two obese parents on markers of adult offspring metabolism, with a focus on body mass (BM), lipid and carbohydrate, components of lipogenesis and beta-oxidation in the liver, sex dimorphism in the offspring that received a SC diet during the postnatal period. MATERIALS AND METHODS Male and female C57BL/6 mice were fed a high-fat diet (HF; 49% lipids) or standard chow (SC; 17% lipids) for 8 weeks before… CONTINUE READING
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