Programming biomolecular self-assembly pathways

@article{Yin2008ProgrammingBS,
  title={Programming biomolecular self-assembly pathways},
  author={P. Yin and H. M. Choi and C. R. Calvert and N. Pierce},
  journal={Nature},
  year={2008},
  volume={451},
  pages={318-322}
}
In nature, self-assembling and disassembling complexes of proteins and nucleic acids bound to a variety of ligands perform intricate and diverse dynamic functions. In contrast, attempts to rationally encode structure and function into synthetic amino acid and nucleic acid sequences have largely focused on engineering molecules that self-assemble into prescribed target structures, rather than on engineering transient system dynamics. To design systems that perform dynamic functions without human… Expand
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