Programmed dissociation of dimer and trimer origami structures by aptamer-ligand complexes.

@article{Wu2017ProgrammedDO,
  title={Programmed dissociation of dimer and trimer origami structures by aptamer-ligand complexes.},
  author={Na Qiong Wu and Itamar Willner},
  journal={Nanoscale},
  year={2017},
  volume={9 4},
  pages={
          1416-1422
        }
}
Dimer- and trimer-origami frames are bridged by duplexes that include caged, sequence-specific, anti-ATP and/or anti-cocaine aptamer sequences. The programmed dissociation of the origami dimers or trimers in the presence of ATP and/or cocaine ligands is demonstrated. The processes are followed by AFM imaging and by electrophoretic experiments.