Programmed death 1 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia.

@article{Xerri2008ProgrammedD1,
  title={Programmed death 1 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia.},
  author={L. Xerri and B. Chetaille and Nacer Serriari and Coralie Attias and Yves Guillaume and C. Arnoulet and D. Olive},
  journal={Human pathology},
  year={2008},
  volume={39 7},
  pages={
          1050-8
        }
}
  • L. Xerri, B. Chetaille, +4 authors D. Olive
  • Published 2008
  • Biology, Medicine
  • Human pathology
  • Programmed death 1 (PD-1) is a lymphoid receptor that negatively regulates immune responses. PD-1 expression was recently reported in some T-cell non-Hodgkin lymphoma (NHL) subtypes, but the expression profile of PD-1 and its ligands (PD-L1 and PD-L2) in B-NHLs remains largely to be characterized. To investigate this issue, monoclonal antibodies against PD-1, PD-L1, and PD-L2 were generated by immunization of balb-c mice. A series of 161 lymphoma tissue and 11 blood samples was analyzed using… CONTINUE READING
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