Programmed death-1 gene polymorphism (PD-1.5 C/T) is associated with gastric cancer

@inproceedings{Savabkar2013ProgrammedDG,
  title={Programmed death-1 gene polymorphism (PD-1.5 C/T) is associated with gastric cancer},
  author={Sanaz Savabkar and Pedram Azimzadeh and Vahid Chaleshi and Ehsan Nazemalhosseini Mojarad and Hamid Asadzadeh Aghdaei},
  booktitle={Gastroenterology and hepatology from bed to bench},
  year={2013}
}
AIM This study aimed to determine the association between PD-1.5C/T (rs2227981, +7785) and the risk of gastric cancer (GC) in an Iranian population. BACKGROUND Gastric cancer is the fourth most common cancer in the world. The programmed death 1 (PD-1) is a member of the CD28 super family. PD-1 is a negative regulator of T-cell effector mechanisms which decrease immune responses against cancer. PATIENTS AND METHODS we conducted case- control study to investigate the association of PD-1.5 C/T… CONTINUE READING