Programmed cell death in the regenerating deer antler.

  title={Programmed cell death in the regenerating deer antler.},
  author={M Colitti and Steven P Allen and Joanne S Price},
  journal={Journal of anatomy},
  volume={207 4},
Antlers are the only mammalian appendages capable of epimorphic regeneration and thus provide a unique model for investigating the mechanisms that underlie mammalian regeneration. Antlers elongate by a modified endochondral ossification process while intramembranous ossification takes place concurrently around the antler shaft. In this study, sites of apoptosis in the growing antler tip were identified by TUNEL staining and related to cell proliferation, as determined by PCNA staining. Bcl-2… CONTINUE READING


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