Programmed cell death in the developing somites is promoted by nerve growth factor via its p75(NTR) receptor.

@article{Cotrina2000ProgrammedCD,
  title={Programmed cell death in the developing somites is promoted by nerve growth factor via its p75(NTR) receptor.},
  author={Maria Luisa Cotrina and M Gonz{\'a}lez-Hoyuela and Julio A. Barbas and Alfredo Rodr{\'i}guez-T{\'e}bar},
  journal={Developmental biology},
  year={2000},
  volume={228 2},
  pages={326-36}
}
Neurotrophins control neuron number during development by promoting the generation and survival of neurons and by regulating programmed neuronal death. In the latter case, the cell death induced by nerve growth factor (NGF) in the developing chick retina is mediated by p75(NTR), the common neurotrophin receptor (J. M. Frade, A. Rodriguez-Tebar, and Y.-A. Barde, 1996, Nature 383, 166-168). Here we show that NGF also induces the programmed death of paraxial mesoderm cells in the developing… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…