Programmed cell death during neuronal development: the sympathetic neuron model

Abstract

Developing sympathetic neurons of the superior cervical ganglion are one of the best studied models of neuronal apoptosis. These cells require nerve growth factor (NGF) for survival at the time that they innervate their final target tissues during late embryonic and early postnatal development. In the absence of NGF, developing sympathetic neurons die by… (More)
DOI: 10.1038/cdd.2014.47

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