Programmed cell death contributes to postnatal lung development.

  title={Programmed cell death contributes to postnatal lung development.},
  author={Johannes C Schittny and Valentin Djonov and Alan Fine and Peter H. Burri},
  journal={American journal of respiratory cell and molecular biology},
  volume={18 6},
The rat lung undergoes the phase of maturation of the alveolar septa and of the parenchymal microvascular network mainly during the third postnatal week. Speculating that programmed cell death may contribute to the thinning of the alveolar septa, we searched for the presence of DNA fragmentation in rat lungs between postnatal days 6 and 36 using the TUNEL procedure. The number of positive nuclei was compared at different days. We observed an 8-fold increase of programmed cell death toward the… CONTINUE READING
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Structural aspects of pre- and postnatal development and growth of the lung

  • P. H. Burri
  • In Growth and Development of the Lung. J…
  • 1997

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