Programmed cell death as a target to interrupt the aging program

  title={Programmed cell death as a target to interrupt the aging program},
  author={Fedor F Severin and Vladimir P. Skulachev},
  journal={Advances in Gerontology},
There are two opposite points of view on aging of organisms. The traditional concept assumes that aging is a stochastic process consisting in age-dependent accumulation of random injuries in living systems. However, many pieces of evidence are recently obtained in favor of an alternative scheme suggesting that aging is genetically programmed being the final step of ontogenesis. The latter concept predicts (i) the existence of non-aging species which have lost the aging program and (ii) that the… 

Contemporary views on human aging and longevity

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  • V. Skulachev
  • Biology
    Annals of the New York Academy of Sciences
  • 2002
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Natural causes of programmed death of yeast Saccharomyces cerevisiae.

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Programmed Death in Bacteria

  • K. Lewis
  • Biology
    Microbiology and Molecular Biology Reviews
  • 2000
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Apoptotic death of ageing yeast

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