Programmed cell death as a mechanism of CD4 and CD8 T cell deletion in AIDS. Molecular control and effect of highly active anti-retroviral therapy.

@article{Gougeon1999ProgrammedCD,
  title={Programmed cell death as a mechanism of CD4 and CD8 T cell deletion in AIDS. Molecular control and effect of highly active anti-retroviral therapy.},
  author={M L Gougeon and Luc Montagnier},
  journal={Annals of the New York Academy of Sciences},
  year={1999},
  volume={887},
  pages={199-212}
}
Infection with human immunodeficiency virus (HIV) results in the progressive destruction of CD4 T lymphocytes, generally associated with progression of the disease. The progressive disappearance of CD4 T lymphocytes leads to the lack of control of HIV replication and to the development of severe immune deficiency responsible for the occurrence of… CONTINUE READING