Programmed cell death (apoptosis) in Alzheimer's disease and Creutzfeldt-Jakob disease.

@article{JesionekKupnicka1997ProgrammedCD,
  title={Programmed cell death (apoptosis) in Alzheimer's disease and Creutzfeldt-Jakob disease.},
  author={Dorota Jesionek-Kupnicka and Jarosław Bucz{\'y}nski and Radzisław Kordek and Tomasz Sobow and Iwona Kłoszewska and Wielisław Papierz and Pawel P. Liberski},
  journal={Folia neuropathologica},
  year={1997},
  volume={35 4},
  pages={
          233-5
        }
}
The aim of our study was the estimation of the apoptosis process using in situ-end labelling of DNA breaks method on paraffin sections in 5 human cases of Alzheimer's disease (AD), 6 of Creutzfeldt-Jakob disease (CJD) and in 25 mice infected experimentally with the Fujisaki strain of CJD, killed sequentially at one-week intervals. The numbers of apoptotic cells in CJD-infected mice in the later stages of the disease and in terminally ill mice were progressively higher that at the early stage of… CONTINUE READING

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