Programmed cell death (apoptosis) in immunity and haematological neoplasia.

  title={Programmed cell death (apoptosis) in immunity and haematological neoplasia.},
  author={Paul D. Allen and Stephen Bustin and Marion G Macey and D H Johnston and Nicola Williams and Adrian C. Newland},
  journal={British journal of biomedical science},
  volume={50 2},
Programmed cell death, also commonly referred to as apoptosis, is a genetically controlled sequence of events, often requiring protein synthesis, which results in cell death. Although initially described 20 years ago, it is only recently that its role as a mechanism in controlling cell population size and content has been fully realised. In this review the biochemical events of apoptosis are discussed briefly, followed by a more detailed look at the role of programmed cell death in the control… CONTINUE READING