Programmed Cell Death in Neuronal Development

  title={Programmed Cell Death in Neuronal Development},
  author={M. Dekkers and Yves-Alain Barde},
  pages={39 - 41}
  • M. Dekkers, Yves-Alain Barde
  • Published 2013
  • Biology, Medicine
  • Science
  • Life or death decisions in cortical interneurons during development are made independently of external cues, challenging current theory. Programmed cell death, or apoptosis, accompanies the development of many tissues, including the vertebrate nervous system. Most neurons are eliminated soon after synaptic contacts have been made between the neurons and their targets. This inspired the neurotrophic theory, which proposes that neurons compete for limited quantities of target-derived survival… CONTINUE READING
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