Programmed Cell Death during Regression of PC-82 Human Prostate Cancer following Androgen Ablation 1

@inproceedings{Kyprianou2006ProgrammedCD,
  title={Programmed Cell Death during Regression of PC-82 Human Prostate Cancer following Androgen Ablation 1},
  author={Natasha Kyprianou and Hugh F. English and John T Isaacs},
  year={2006}
}
To study the mechanism of regression of human prostatic cancer following androgen ablation, the androgen-responsive PC-82 human pros tatic adenocarcinoma xenograft was used as a model system. Castration of male nude mice bearing PC-82 xenografts results in a 50' i tumor regression by 2 wk following androgen ablation. This regression is due to a sequence of biochemical and morphological events that results in both the cessation of cell proliferation and activation of programmed death or… CONTINUE READING

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