Programmed Cell Death 5 from Toxoplasma gondii: a secreted molecule that exerts a pro-apoptotic effect on host cells.

@article{Bannai2008ProgrammedCD,
  title={Programmed Cell Death 5 from Toxoplasma gondii: a secreted molecule that exerts a pro-apoptotic effect on host cells.},
  author={Hiroshi Bannai and Yoshifumi Nishikawa and Tomohide Matsuo and Osamu Kawase and Junichi Watanabe and Chihiro Sugimoto and Xuenan Xuan},
  journal={Molecular and biochemical parasitology},
  year={2008},
  volume={159 2},
  pages={112-20}
}
Although parasite-infected host cells become resistant to apoptosis, uninfected bystander cells undergo apoptosis during Toxoplasma gondii infection. The Programmed Cell Death 5 (TgPDCD5) gene, a homologue of the human apoptosis-related molecule, was cloned from a T. gondii full-length cDNA database and subsequently characterized. The native TgPDCD5 was… CONTINUE READING