Programmable engineering of a biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection.


Self-assembled DNA nanostructures with precise sizes allow a programmable "soft lithography" approach to engineer the interface of electrochemical DNA sensors. By using millimeter-sized gold electrodes modified with several types of tetrahedral DNA nanostructures (TDNs) of different sizes, both the kinetics and thermodynamics of DNA hybridization were… (More)
DOI: 10.1002/anie.201410720


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