Prognostic value of uPA, PAI-1, and DNA content in adult renal cell carcinoma.

@article{Chautard2004PrognosticVO,
  title={Prognostic value of uPA, PAI-1, and DNA content in adult renal cell carcinoma.},
  author={Denis Chautard and Isabelle Dalifard and Agn{\`e}s Chassevent and Serge Guy{\'e}tant and Alain Daver and Bruno Vielle and Jean Yves Soret},
  journal={Urology},
  year={2004},
  volume={63 6},
  pages={1055-60}
}
OBJECTIVES To examine whether urokinase-type plasminogen activator (uPA) and type 1 plasminogen inhibitor (PAI-1), DNA ploidy, and S-phase fraction (SPF) add supplementary prognostic information relative to stage and Fuhrman's grade in renal cell carcinoma. METHODS A total of 100 patients with primary renal adenocarcinoma treated by nephrectomy were followed up for a median of 42 months. Of the 100 patients, 78 with Stage M0N0-Nx tumors were studied by multivariate analysis. The study… CONTINUE READING