Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers.

@article{Jiang2003PrognosticVO,
  title={Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers.},
  author={Wen Jiang and Gareth Watkins and Jane Lane and Giles H. Cunnick and Anthony G Douglas-Jones and Kefah Mokbel and Robert E. Mansel},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2003},
  volume={9 17},
  pages={6432-40}
}
PURPOSE Rho family members are small GTPases that are known to regulate malignant transformation and motility of cancer cells. The activities of Rhos are regulated by molecules such as guanine nucleotide dissociation inhibitors (GDIs). This study determined the levels of expression and the distribution of Rho-A, -B, -C, and -G, and Rho-6, -7, and -8, as well as Rho-GDI-beta, and Rho-GDI-gamma, in breast cancer and assessed their prognostic value. EXPERIMENTAL DESIGN The distribution and… CONTINUE READING
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Level of expression of PPAR- and its co-activator (PPAR-GCA) in human breast cancer

  • W. G. Jiang, A. Douglas-Jones, R. E. Mansel
  • Int. J. Cancer,
  • 2003

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