Prognostic value of neurohormonal activation and cardiopulmonary exercise testing in patients with chronic heart failure.

@article{Isnard2000PrognosticVO,
  title={Prognostic value of neurohormonal activation and cardiopulmonary exercise testing in patients with chronic heart failure.},
  author={Richard Isnard and Françoise Pousset and Jean-no{\"e}l Trochu and Olga Chafirovska{\"i}a and Alain Carayon and J. L. Golmard and Ph Lechat and Dani{\`e}l Thomas and J B Bouhour and Michel Komajda},
  journal={The American journal of cardiology},
  year={2000},
  volume={86 4},
  pages={417-21}
}
We compared the value of plasma neurohormones and cardiopulmonary exercise testing for predicting long-term prognosis in patients with moderate congestive heart failure (CHF). We studied 264 consecutive patients with CHF due to left ventricular systolic dysfunction. Plasma atrial natriuretic peptide (ANP), norepinephrine, and endothelin-1 were measured at rest in all patients, who also underwent a symptom-limited maximal exercise with oxygen consumption (VO(2)) determination. After a median… CONTINUE READING

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