Prognostic value of intratumoral interferon gamma messenger RNA expression in invasive cervical carcinomas.
@article{Tartour1998PrognosticVO,
title={Prognostic value of intratumoral interferon gamma messenger RNA expression in invasive cervical carcinomas.},
author={Eric Tartour and Alain Gey and Xavier Sastre-Garau and I Lombard Surin and Véronique Mosseri and Wolf Herman Fridman},
journal={Journal of the National Cancer Institute},
year={1998},
volume={90 4},
pages={
287-94
}
}BACKGROUND
The production of the cytokine interferon gamma (IFN gamma) by activated peripheral blood mononuclear cells may be reduced in patients with invasive cervical carcinoma. This study was designed to assess the prognostic value of intratumoral IFN gamma messenger RNA (mRNA) levels in such patients.
METHODS
Biopsy specimens of primary cervical lesions were obtained from 27 patients with invasive squamous cell carcinoma before they received any therapy. Two prognostic groups were…
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