Prognostic value of decreased expression of RBM4 in human gastric cancer

  title={Prognostic value of decreased expression of RBM4 in human gastric cancer},
  author={H. Yong and H. Zhu and Shu Zhang and W. Zhao and Weiguang Wang and Chen Chen and Guipeng Ding and Lun Zhu and Ziyuan Zhu and H. Liu and Yongjie Zhang and Jin Wen and X. Kang and J. Zhu and Zhenqing Feng and B. Liu},
  journal={Scientific Reports},
RNA-binding motif 4 (RBM4) is a multifunctional protein that participates in regulating alternative splicing and mRNA translation. Its reduced expression has been associated with poor overall survival in lung cancer, breast cancer and ovarian cancer. We assessed RBM4 protein expression levels with immunohistochemistry in tissue microarrays containing malignant gastric cancer tissues and benign tissues from 813 patients. We also examined the expression levels of RBM4 mRNA in twenty-five paired… Expand
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