Prognostic value of cyclin B1 in patients with esophageal squamous cell carcinoma.

@article{Takeno2002PrognosticVO,
  title={Prognostic value of cyclin B1 in patients with esophageal squamous cell carcinoma.},
  author={Shinsuke Takeno and Tsuyoshi Noguchi and Ryuichi Kikuchi and Yuzo Uchida and Shigeo Yokoyama and Wolfram Mueller},
  journal={Cancer},
  year={2002},
  volume={94 11},
  pages={2874-81}
}
BACKGROUND It has been reported that p53 regulates the G2-M checkpoint transition through cyclin B1, and it has been suggested that p53 plays an important role in the development and progression of various malignancies. The objective of the current study was to clarify the role of the cell cycle regulators, cyclin B1 and p53, in patients with esophageal squamous cell carcinoma (ESCC). METHODS Tissue samples from 71 patients with ESCC were included in the current study. Expression levels of… CONTINUE READING