Prognostic value of PCSK9 levels in patients with acute coronary syndromes.

  title={Prognostic value of PCSK9 levels in patients with acute coronary syndromes.},
  author={Bariş Gencer and Fabrizio Montecucco and David Nanchen and Federico Carbone and Roland Klingenberg and Nicolas Vuilleumier and Soheila Aghlmandi and Dik Heg and Lorenz Raeber and Reto Auer and Peter J{\"u}ni and Stephan Windecker and Thomas F L{\"u}scher and Christian M Matter and Nicolas Rodondi and François Mach},
  journal={European heart journal},
  volume={37 6},
AIMS Proprotein convertase subtilisin kexin 9 (PCSK9) is an emerging target for the treatment of hypercholesterolaemia, but the clinical utility of PCSK9 levels to guide treatment is unknown. We aimed to prospectively assess the prognostic value of plasma PCSK9 levels in patients with acute coronary syndromes (ACS). METHODS AND RESULTS Plasma PCSK9 levels were measured in 2030 ACS patients undergoing coronary angiography in a Swiss prospective cohort. At 1 year, the association between PCSK9… CONTINUE READING
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