Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.

@article{Koot1993PrognosticVO,
  title={Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.},
  author={M. Koot and Ireneus P. M. Keet and Allert H. Vos and R E de Goede and Marijke Th L Roos and Roel A. Coutinho and Felicia Miedema and Peter Th A Schellekens and Matthijs Tersmette},
  journal={Annals of internal medicine},
  year={1993},
  volume={118 9},
  pages={
          681-8
        }
}
The human immunodeficiency virus type 1 (HIV-1) causes a chronic infection in humans that is characterized by a gradual depletion of CD4+ T cells [1]. After an asymptomatic period of variable length, a large proportion of infected patients develop the acquired immunodeficiency syndrome (AIDS) [2]. Detailed virologic and immunologic studies have shown that AIDS is the final stage of a disease process that is continuously active from the moment of infection [3-9]. Thus, an increasing tendency… CONTINUE READING

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