Prognostic value of ERCC1 in head and neck carcinoma treated with definitive or adjuvant radiotherapy

@article{Biof2012PrognosticVO,
  title={Prognostic value of ERCC1 in head and neck carcinoma treated with definitive or adjuvant radiotherapy},
  author={Vesna Bi{\vs}of and Antonija Jakov{\vc}evi{\'c} and Sven Seiwerth and Zoran Raku{\vs}i{\'c} and Slavko Ga{\vs}parov},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2012},
  volume={139},
  pages={187-194}
}
PurposeTo evaluate the prognostic significance of excision repair cross-complementation group 1 (ERCC1) expression in head and neck carcinoma patients treated with definitive radiotherapy (DR) or adjuvant radiotherapy (AR).MethodsERCC1 expression was assessed by immunohistochemical staining. A total of 48 patients were assessed.ResultsHigh ERCC1 expression was found in 23 patients (48 %). More ERCC1-positive tumours were detected in patients treated with DR than in patients treated with AR (73… CONTINUE READING
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