Prognostic value and clinicopathological profile of microsatellite instability in gastric cancer.

@article{Wirtz1998PrognosticVA,
  title={Prognostic value and clinicopathological profile of microsatellite instability in gastric cancer.},
  author={Heiner Wirtz and Wolfram Mueller and Tsuyoshi Noguchi and Melanie Scheven and Joseph Rueschoff and G. Hommel and Helmut Erich Gabbert},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1998},
  volume={4 7},
  pages={1749-54}
}
In this study, microsatellite instability (MI) was investigated in 126 gastric carcinomas and correlated with clinicopathological features and prognosis; at least 5-10 microsatellite loci were analyzed. MI was identified in 56 (44.5%) of all investigated carcinomas, one locus being affected in 40 (31.7%) carcinomas, two loci being affected in 6 (4.8%) carcinomas, and more than two loci being affected in 10 (8.0%) carcinomas. MI was correlated with neither age and sex of the patients nor with… CONTINUE READING
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