Prognostic significance of tumor infiltrating lymphocytes in melanoma.

  title={Prognostic significance of tumor infiltrating lymphocytes in melanoma.},
  author={Alison L Burton and Brent A Roach and Michael P Mays and Andrea F Chen and Brooke A R Ginter and Abbey M Vierling and Charles Raben Scoggins and Robert C. Martin and Arnold J. Stromberg and Lee J Hagendoorn and Kelly M. McMasters},
  journal={The American surgeon},
  volume={77 2},
The prognostic significance of tumor infiltrating lymphocyte (TIL) response in cutaneous melanoma is controversial. This analysis of data from a prospective, randomized trial included patients with cutaneous melanoma > or = 1.0 mm Breslow thickness who underwent wide local excision and sentinel lymph node (SLN) biopsy. Univariate and multivariate analyses were performed to determine factors associated with TIL response, disease-free survival (DFS), and overall survival (OS). A total of 515… CONTINUE READING