Prognostic significance of stromelysin 3, gelatinase A, and urokinase expression in breast cancer.

@article{Ttu1998PrognosticSO,
  title={Prognostic significance of stromelysin 3, gelatinase A, and urokinase expression in breast cancer.},
  author={Bernard T{\^e}tu and Jacques Brisson and H{\'e}l{\`e}ne Lapointe and P P Bernard},
  journal={Human pathology},
  year={1998},
  volume={29 9},
  pages={979-85}
}
This study was aimed at testing the hypothesis that the expression of proteases essentially produced by reactive stromal cells (stromelysin-3 [ST3], gelatinase A [GELA], and urokinase [uPA]) is predictive of prognosis in patients with breast cancer. This was a study of patients with node-positive and node-negative breast cancer diagnosed from 1980 to 1986 and with an average of 10 years follow-up. ST3 (665 cases), GELA, and uPA (575 cases each) expression was obtained by in situ hybridization… CONTINUE READING